Dewi was graduated  in 1991 from Department of Architecture, Bandung Institute of Technology (ITB). After staying in Germany for short course in 1992-1993, then she was joined in Fortune Indonesia Goup of Companies which its line of bussiness is in Integrated Communications. Now she is one of the Director of PT. Fortune Adwicipta, a subsidiary company of PT. Fortune Indonesia Tbk.

After graduated from Law School of the University of Indonesia, Karini worked in Central for Legal Studies and was involved in law research in Indonesia and the United States. Following years of research, she started legal practice in law firms and public listed companies.  In 2004, she and some of her colleagues established a corporate law firm, Wahyu Nugroho Legal Practice, in which she is now an advisor.

Karina is an entrepreneur and has an education background in economy.  With her partners, she has set up PT Wahana Boga which engages in café and restaurants business.  She is a director and owner of PT Panca Mitra Karsa, a real estate company.  She has also actively involved in construction works at PT Komponindo Bentonjaya for many years.